- Q REMASTERED (Switch eShop)
- Q*Bert (Arcade)
- Q*Bert (GB)
- Q-Bert (GBC)
- Q-YO Blaster (Switch eShop)
- Q.U.B.E. 10th Anniversary (Switch eShop)
- Q.U.B.E. 2 (Switch eShop)
- Q.U.B.E: Director's Cut (Wii U eShop)
- Q2 Humanity (Switch eShop)
- QB Planets (Switch eShop)
- Qbics Paint (Switch eShop)
- Qbik (Switch eShop)
- QBillion (GB)
- QIX (GB)
- Qix Adventure (GBC)
- qomp2 (Switch eShop)
- qrth-phyl (Switch eShop)
- Quack Jump (Switch eShop)
- Quad Fighter K (Switch eShop)
- Quadcopter Pilot Challenge (Wii U eShop)
- Quadle (Switch eShop)
- Quadroids (Switch eShop)
- Quake (N64)
- Quake (Switch eShop)
- Quake + Quake II Enhanced Bundle (Switch eShop)
- Quake II (N64)
- Quake II (Switch eShop)
- QUALIA ~The Path of Promise~ (Switch eShop)
- Quantum League (Switch eShop)
- Quantum Replica (Switch eShop)
- Quantum Storm (Switch eShop)
- Quantum: Recharged (Switch eShop)
- Quarantine Circular (Switch eShop)
- Quarry Truck Simulator (Switch eShop)
- Quartet (Arcade)
- Quartet 2 (Arcade)
- Quarth (GB)
- Qube Qross (Switch eShop)
- QUByte Classics - The Humans by PIKO (Switch eShop)
- QUByte Classics - The Immortal by PIKO (Switch eShop)
- QUByte Classics: Jim Power: The Lost Dimension by PIKO (Switch eShop)
- QUByte Classics: Thunderbolt Collection by PIKO (Switch eShop)
- Queen's Garden (Wii U eShop)
- Queen's Garden - Sakura Season (Switch eShop)
- Queen's Quest 2: Stories of Forgotten Past (Switch eShop)
- Queen's Quest 3: The End of Dawn (Switch eShop)
- Queen's Quest 4: Sacred Truce (Switch eShop)
- Queeny Army (Switch eShop)
- Quell (Switch eShop)
- Quell Memento (3DS eShop)
- Quell Memento (Switch eShop)
- Quell Reflect (3DS eShop)
- Quell Reflect (Switch eShop)
- Quell Zen (Switch eShop)
- Quench (Switch eShop)
- Quest 64 (N64)
- Quest for Camelot (GBC)
- Quest for Infamy (Switch eShop)
- Quest for the Golden Duck (Switch eShop)
- Quest Hunter (Switch eShop)
- Quest Hunter: Deluxe Edition (Switch eShop)
- Quest Master (Switch eShop)
- Quest of Dungeons (3DS eShop)
- Quest of Dungeons (Switch eShop)
- Quest of Dungeons (Wii U eShop)
- Quest: Brian's Journey (GBC)
- Quest: Fantasy Challenge (GBC)
- Quick Fill Q (DSiWare)
- Quick Golf (Switch eShop)
- Quick Race (Switch eShop)
- Quick Yoga Training (DS)
- Quick, Quack! (Switch eShop)
- QuickPick Farmer (DSiWare)
- QuickSpot (DS)
- QuickSpot (Switch eShop)
- Quiet, Please! (3DS eShop)
- QuietMansion1 (Switch eShop)
- Quilts & Cats of Calico (Switch eShop)
- Quintus and the Absent Truth (Switch eShop)
- Quiplash (Switch eShop)
- Quiplash 2 InterLASHional: The Say Anything Party Game! (Switch eShop)
- Quiz & Dragons: Capcom Quiz Game (Arcade)
- Quiz 4 All (Switch eShop)
- QUIZ 50 Ways to Read the KANJI 生 (Switch eShop)
- Quiz Magic Academy DS (DS)
- Quiz Magic Academy DS: Futatsu no Jik?seki (DS)
- Quiz Nanairo Dreams: Nijiiro-chou no Kiseki (Arcade)
- Quiz Party (Wii)
- Quiz Tonosama no Yabou 2 Zenkoku-ban (Arcade)
- QUIZ! Cat Proverbs Around the World (Switch eShop)
- Qupu!! Mame Goma! (DS)
- QV (Switch eShop)
- QwikWits (Switch eShop)